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Postdoctoral scholarship in transcriptional regulation by metal-sensing AP-1 proteins

Nyhet: 2018-01-10

We hereby announce that one post-doctoral stipend is available at the Department of Chemistry and Molecular Biology, University of Gothenburg.

Project description: The project concerns the molecular details of metalloid sensing and signaling by yeast AP-1-like transcription factors. More specifically, you will decipher how the transcription factors Yap1 and Yap8 - first arsenic sensor proteins described in eukaryotes - couple metalloid-binding with the activation of detoxification systems.

Competence: We seek a talented and dedicated postdoctoral fellow eager to pursue a career in microbiology/molecular biology. You should be open-minded, eager to learn and have a genuine interest in Science. You should be able to work independently and in a team and communicate well in English. The ideal candidate should have documented research experience in molecular biology or biochemistry. Experience with yeast, gene expression and/or transcription factors is considered an advantage. Candidates should either hold a Ph.D. degree (obtained not more than two years ago) or obtain it before the start of the project.

About us: Markus Tamás' research group has an interest in the molecular basis of metal toxicity and detoxification. The team investigates (1) transport proteins through which metals enter or leave cells, (2) signal transduction and transcriptional regulatory mechanisms that cells use to sense and respond to metals, and (3) proteins and cellular processes that are targeted by metals. Tamás uses budding yeast (S. cerevisiae) to elucidate fundamental aspects of metal biology and as a heterologous expression system to study tolerance factors from other organisms such as plants, parasites and mammals. For more information: http://www.gu.se/staff/markustamas; Markus Tamás at scholar.google.se

Research environment: Yeast functional genomics and cell biology is a strong research area at the department of Chemistry & Molecular Biology (CMB) and the participating research groups are highly interactive and share technology platforms for high-throughput genetics and cell biology. Thus, CMB provides an excellent environment for successful interdisciplinary research in the life sciences and an outstanding training ground for students and postdocs in microbiology.

Reference number: Dnr E 2018/11

Scholarship period: The scholarship covers a period of 12 months with possibility of prolongation up to a maximum of 24 months in total.

Preliminary start date: as early as possible in 2018

Supervisor/contact person: Prof. Markus Tamás; telephone number: +46-73-373 2548; e-mail: markus.tamas@cmb.gu.se

• To be eligible for a post-doc scholarship at the recipient must hold a PhD degree within a relevant field. The applicant must not have been employed at University of Gothenburg in the past two years.
• Please specify experiences, knowledge or interests necessary for taking part as a postdoc in this project. Remember that a scholarship is not an employment and the qualifications necessary might differ from what you could ask for from an employee.

Written application, including reference number, is to be sent via e-mail to the supervisor and must include the following:
• CV
• Personal letter stating the reasons why the study suits the applicant (maximum one page)
• List of publications
• Letters of reference (2)

Application deadline: 2018-02-15

Information regarding scholarships:
• Scholarships do not give rise to sickness benefits, compensation from the Social Insurance Office or retirement pension.
• The scholarship sum is paid out quarterly
• Scholarships are tax-exempt
• A scholarship holder cannot be hired after the scholarship period due to tax reasons.


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