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Gergely Katona

Professor

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Gergely Katona
Professor
gergely.katona@cmb.gu.se
+46 31 786 3959
0709-123309

Room number: 1213
Postal Address: Box 462, 40530 Göteborg
Visiting Address: Medicinaregatan 9C , 41390 Göteborg


Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
www.cmb.gu.se
inst.kmb@cmb.gu.se
Fax: +46 31 786 2599
Visiting Address: Medicinaregatan 9 C , 413 90 Göteborg

About Gergely Katona

Crystallographic investigations usually focus on the resting state of proteins. The technical limitation of this technique makes it difficult to study proteins and enzymes at work. Chemical and physical triggering and trapping techniques allow the investigation of reacting enzyme at different intermediate states. Once stabilized, these states can be studied with different X-ray techniques. The benefit of these studies is on one hand the development of the techniques which can be used for studying enzymes engaged in catalytic activity and on the other hand the results contribute to a better understanding of how a specific enzyme functions. You can find more information about Gergely's research at http://katonalab.eu

Gergely is the course coordinator for the course "Biomolecular Structure and Dynamics" (KEM360). KEM360 has biophysical methods in focus (crystallography, SAXS, NMR, EM, vibration spectroscopy) and develops the skills to conduct research in integrated structural biology. Students have the opportunity to visit MaxIV and gain practical experience with electron microscopy and NMR.

Gergely also teaches in the courses:

  • KEM350 (Design and Production of Biomolecules),
  • KEM011 (Basic Chemistry),
  • KER210 (Analytical pharmaceutical chemistry),
  • KER220 (General pharmaceutical chemistry),
  • KEM131 (Colloid and Surface Chemistry) and
  • KMB056 (Molecular Biotechnology).

Gergely supervises doctoral students, Master and Bachelor students, with training focus on method development and universal skills to conduct independent research.

Gergely reviews applications to the iNEXT network and beamlines at EMBL Hamburg. Gergely participates in a LINXS working group (http://www.linxs.se).

CV

Research areas

Major publications

Bayesian Analysis of MicroScale Thermophoresis Data to Quantify Affinity of Protein:Protein Interactions with Human Survivin.
Maria-Jose Garcia-Bonete, Maja Jensen, Christian V Recktenwald, Sandra Rocha, Volker Stadler et al.
Scientific reports, 2017

Read the full text
on a web page

Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystal
Ida Lundholm, Helena Rodilla, Weixiao Yuan Wahlgren, Annette Duelli, Gleb Bourenkov et al.
Structural Dynamics, 2015

Read the full text
on a web page

Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
Lars Redecke, Karol Nass, Daniel P DePonte, Thomas A White, Dirk Rehders et al.
Science (New York, N.Y.), 2013

Read the full text
on a web page

Latest publications

A tool for visualizing protein motions in time-resolved crystallography
Cecilia Wickstrand, Gergely Katona, T. Nakane, P. Nogly, J. Standfuss et al.
Structural Dynamics-Us, Journal article 2020
Journal article

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on a web page

In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors
K. Nass, L. Redecke, M. Perbandt, O. Yefanov, M. Klinge et al.
Nature Communications, Journal article 2020
Journal article

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on a web page

Clustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties.
Viktor Ahlberg Gagnér, Ida Lundholm, Maria-Jose Garcia-Bonete, Helena Rodilla, Vitali Zhaunerchyk et al.
Scientific reports, Journal article 2019
Journal article

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on a web page

Bayesian machine learning improves single-wavelength anomalous diffraction phasing
Maria-Jose Garcia-Bonete, Gergely Katona
Acta Crystallographica a-Foundation and Advances, Journal article 2019
Journal article

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on a web page

A practical guide to developing virtual and augmented reality exercises for teaching structural biology.
Maria-Jose Garcia-Bonete, Maja Jensen, Gergely Katona
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, Journal article 2019
Journal article

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on a web page

Bayesian Analysis of MicroScale Thermophoresis Data to Quantify Affinity of Protein:Protein Interactions with Human Survivin.
Maria-Jose Garcia-Bonete, Maja Jensen, Christian V Recktenwald, Sandra Rocha, Volker Stadler et al.
Scientific reports, Journal article 2017
Journal article

Read the full text
on a web page

Survivin in autoimmune diseases.
Giacomo Gravina, Caroline Wasén, Maria-Jose Garcia-Bonete, Minna Turkkila, Malin Erlandsson et al.
Autoimmunity reviews, Review article 2017
Review article

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on a web page

Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Péter Ecsédi, Bence Kiss, Gergő Gógl, László Radnai, László Buday et al.
Structure (London, England : 1993), Journal article 2017
Journal article

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on a web page

Asymmetry in serial femtosecond crystallography data
Amit Sharma, Linda C Johansson, Elin Dunevall, Weixiao Yuan Wahlgren, Richard Neutze et al.
Acta Crystallographica a-Foundation and Advances, Journal article 2017
Journal article

Read the full text
on a web page

Bayesian analysis of non-thermal structural changes induced by terahertz radiation in protein crystals
Gergely Katona, Ida Lundholm, H. Rodilla, Maria-Jose Garcia-Bonete, Annette Duelli et al.
41st International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). SEP 25-30, 2016 .Copenhagen, Denmark., New York, IEEE, Conference paper 2016
Conference paper

Major publications

Bayesian Analysis of MicroScale Thermophoresis Data to Quantify Affinity of Protein:Protein Interactions with Human Survivin.
Maria-Jose Garcia-Bonete, Maja Jensen, Christian V Recktenwald, Sandra Rocha, Volker Stadler et al.
Scientific reports, 2017

Read the full text
on a web page

Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystal
Ida Lundholm, Helena Rodilla, Weixiao Yuan Wahlgren, Annette Duelli, Gleb Bourenkov et al.
Structural Dynamics, 2015

Read the full text
on a web page

Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
Lars Redecke, Karol Nass, Daniel P DePonte, Thomas A White, Dirk Rehders et al.
Science (New York, N.Y.), 2013

Read the full text
on a web page

Showing 21 - 30 of 49

2014

Terahertz absorption of illuminated photosynthetic reaction center solution: a signature of photoactivation?
Ida Lundholm, Weixiao Yuan Wahlgren, F. Piccirilli, P. Di Pietro, Annette Duelli et al.
Rsc Advances, Journal article 2014
Journal article

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on a web page

The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 through Conformational Activation.
Annette Duelli, Bence Kiss, Ida Lundholm, Andrea Bodor, Maxim V Petoukhov et al.
PLoS ONE, Journal article 2014
Journal article

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on a web page

2013

Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography.
Linda C Johansson, David Arnlund, Gergely Katona, Thomas A White, Anton Barty et al.
Nature communications, Journal article 2013
Journal article

Read the full text
on a web page

Comparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor - the key to achieving extreme stability?
Tamás Molnár, Judit Vörös, Bálint Szeder, Kornél Takáts, József Kardos et al.
The FEBS journal, Journal article 2013
Journal article

Read the full text
on a web page

Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
Lars Redecke, Karol Nass, Daniel P DePonte, Thomas A White, Dirk Rehders et al.
Science (New York, N.Y.), Journal article 2013
Journal article

Read the full text
on a web page

2012

Crystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism.
Bence Kiss, Annette Duelli, László Radnai, Katalin A Kékesi, Gergely Katona et al.
Proceedings of the National Academy of Sciences of the United States of America, Journal article 2012
Journal article

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on a web page

Structural Characterization of Bacterioferritin from Blastochloris viridis
Weixiao Yuan Wahlgren, Hadil Omran, D. von Stetten, A. Royant, Sjoerd van der Post et al.
Plos One, Journal article 2012
Journal article

Read the full text
on a web page

Lipidic phase membrane protein serial femtosecond crystallography.
Linda C Johansson, David Arnlund, Thomas A White, Gergely Katona, Daniel P DePonte et al.
Nature methods, Journal article 2012
Journal article

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on a web page

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography
S. Boutet, L. Lomb, G. J. Williams, T. R. M. Barends, A. Aquila et al.
Science, Journal article 2012
Journal article

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on a web page

2011

The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action.
Weixiao Yuan Wahlgren, Gábor Pál, József Kardos, Pálma Porrogi, Borbála Szenthe et al.
The Journal of biological chemistry, Journal article 2011
Journal article

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on a web page

Showing 21 - 30 of 49

Page Manager: Katleen Burm|Last update: 9/20/2013
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