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Markus Tamas

Professor

Markus Tamas
Professor , Head of Department
molecular biology/genetics/biochemistry/yeast
markus.tamas@cmb.gu.se
+46 31 786 2548
0733-732548

Room number: 1450
Postal Address: Box 462, 40530 Göteborg
Visiting Address: Medicinaregatan 9 c , 41390 Göteborg


Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
www.cmb.gu.se
inst.kmb@cmb.gu.se
Fax: +46 31 786 2599
Visiting Address: Medicinaregatan 9 C , 413 90 Göteborg

About Markus Tamas

Contact details: Lundberg Laboratory, Medicinaregatan 9, Room number 1415

 

RESEARCH

Molecular biology of metal toxicity and tolerance

Many metals endanger the environment and human health, but are also increasingly used as therapeutic agents for medical treatment. Yet, little is known about the molecular mechanisms causing metal toxicity or the mechanisms by which eukaryotic cells counteract toxicity and acquire tolerance.
To gain insights into metal action and cellular tolerance mechanisms, we use front-line tools in molecular biology, biochemistry, cell biology, chemical biology and functional genomics. We study (1) transport proteins through which metals enter or leave cells, (2) signal transduction and transcriptional regulatory mechanisms that cells use to sense and respond to metals, and (3) proteins and cellular processes that are targeted by metals. We use the model eukaryote Saccharomyces cerevisiae to explore fundamental aspects of metal biology and also as a heterologous expression system to study tolerance factors from other organisms such as plants and mammals.

Publications ResearcherID: www.researcherid.com/rid/E-8183-2010

Publications Google Scholar: scholar.google.se/citations

Research team: Stefanie Weber (PhD student), Joana Rodrigues (PhD student), Sansan Hua (PhD student), Antonia Romero (postdoc)


TEACHING

  • Eukaryotic Molecular Microbiology (BIO440)
  • Molecular Microbiology (BIO277)
  • Cell biology (BIO900)

 

COMMISSIONS

  • Head of Department: Department of Chemistry and Molecular Biology

 

QUALIFICATIONS

Markus J. Tamás studied molecular biology and biochemistry in Lund (Sweden) and Liège (Belgium) and spent a year as a research scholar at the Public Health Research Institute in New York (USA). Markus completed his PhD at the Katholieke Universiteit Leuven (Belgium) in 1999 and then moved to Gothenburg. Markus was awarded an assistant professorship by the Swedish Research Council in 2003 and became professor in eukaryotic microbiology in 2010.

Latest publications

Editorial: Molecular Mechanisms of Metalloid Transport, Toxicity and Tolerance.
Gerd Patrick Bienert, Markus J. Tamás
Frontiers in cell and developmental biology, Editorial letter 2018
Editorial letter

Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo.
Markus J. Tamás, Bruno Fauvet, Philipp Christen, Pierre Goloubinoff
Current genetics, Review article 2018
Review article

Cadmium Causes Misfolding and Aggregation of Cytosolic Proteins in Yeast.
Therese Jacobson, Smriti Priya, Sandeep K Sharma, Stefanie Andersson, Sofia Jakobsson et al.
Molecular and Cellular Biology, Journal article 2017
Journal article

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.
Nallani Vijay Kumar, Jianbo Yang, Jitesh K Pillai, Swati Rawat, Carlos Solano et al.
Molecular and cellular biology, Journal article 2016
Journal article

Disentangling genetic and epigenetic determinants of ultrafast adaptation.
Arne B Gjuvsland, Enikö Zörgö, Jeevan Ka Samy, Simon Stenberg, Ibrahim H Demirsoy et al.
Molecular systems biology, Journal article 2016
Journal article

The mitogen-activated protein kinase Slt2 modulates arsenite transport through the aquaglyceroporin Fps1.
Doryaneh Ahmadpour, Ewa Maciaszczyk-Dziubinska, Roja Babazadeh, Sita Dahal, Magdalena Migocka et al.
FEBS letters, Journal article 2016
Journal article

HwHog1 kinase activity is crucial for survival of Hortaea werneckii in extremely hyperosmolar environments.
Anja Kejžar, Morten Grøtli, Markus J. Tamás, Ana Plemenitaš, Metka Lenassi
Fungal genetics and biology : FG & B, Journal article 2015
Journal article

Showing 31 - 40 of 76

2010

Yeast cells export glutathione as an extracellular defence mechanism
Therese Jacobson, Michael Thorsen, Rita Vooijs, Henk Schat, Markus J. Tamás
35th FEBS Congress, Gothenburg, Sweden, Poster 2010
Poster

How Saccharomyces cerevisiae copes with toxic metals and metalloids.
Robert Wysocki, Markus J. Tamás
FEMS microbiology reviews, Review article 2010
Review article

Extracellular glutathione protects yeast cells from arsenite toxicity
Michael Thorsen, Therese Jacobson, Rita Vooijs, Henk Schat, Markus J. Tamás
Yeast Genetics and Molecular Biology Meeting, Vancouver, Canada, Poster 2010
Poster

2009

Arsenic resistance in Kluyveromyces lactis
Jenny Veide Vilg, Ewa Maciaszczyk-Dziubinska, Ewa Sloma, Robert Wysocki, Markus J. Tamás
International Conference on Yeast Genetics and Molecular Biology, Manchester, UK, Conference contribution 2009
Conference contribution

Highly selective, cell-permeable and fast-acting wild-type Hog1 inhibitors as tools for studying cellular function of kinases
Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén, Terese Andersson, Stefan Hohmann et al.
Functional Genomics Symposium: Chemical Biology – Molecules to Probe Life, Gothenburg, Sweden, Conference contribution 2009
Conference contribution

Synthesis and use of positional scanning peptide libraries for determination of kinase substrate consensus sequences
Jenny Veide Vilg, Thomas Ljungdahl, Markus J. Tamás, Morten Grøtli
Functional Genomics Symposium: Chemical Biology – Molecules to Probe Life, Gothenburg, Sweden, Conference contribution 2009
Conference contribution

Molecular mechanisms of arsenic toxicity and tolerance
Markus J. Tamás
SMYTE 2009, Blankenberge, Belgium, Conference contribution 2009
Conference contribution

Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae.
Michael Thorsen, Gabriel G Perrone, Erik Kristiansson, Mathew Traini, Tian Ye et al.
BMC genomics, Journal article 2009
Journal article

Extracellular glutathione protects yeast cells from arsenite toxicity
Markus J. Tamás, Michael Thorsen, Therese Jacobson, Rita Vooijs, Henk Schat
FEMS Congress 2009, Gothenburg, Sweden, Conference contribution 2009
Conference contribution

Extracellular glutathione protects yeast cells from arsenite toxicity
Markus J. Tamás, Michael Thorsen, Therese Jacobson, Rita Vooijs, Henk Schat
International Conference on Yeast Genetics and Molecular Biology, Manchester, UK, Conference contribution 2009
Conference contribution

Showing 31 - 40 of 76

Page Manager: Katleen Burm|Last update: 6/20/2016
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