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Leif Eriksson

Professor

Leif Eriksson
Professor
leif.eriksson@chem.gu.se
+46 31 786 9117
0766-229117

Room number: 1405
Postal Address: Box 462, 40530 Göteborg
Visiting Address: Medicinaregatan 9c, Lundberg Lab, , 41390 Göteborg


Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
www.cmb.gu.se
inst.kmb@cmb.gu.se
Fax: +46 31 786 2599
Visiting Address: Medicinaregatan 9 C , 413 90 Göteborg

About Leif Eriksson

Contact information: Lundberg Lab, Medicinareg. 9c, 40530 Göteborg; office 1405.

 

 RESEARCH

Theoretical biophysical chemistry in form of computer based modeling of various biochemical processes and systems. Our focus has for a long time related to DNA damage processes, cancer and drug design; often linked to radical and photochemistry. In recent years, we have explored increasingly larger systems, including diffusion across biological membranes, drug loaded liposomes, derivation of protein structures and studies of their mechanisms, modeling of protein-protein complexes, and development of new inhibitors in cancer treatment and as antibiotics. 

We utilize a wide range of methods in our research, from DFT and QM/MM to molecular dynamics simulations and bioinformatic tools such as VHTS/docking and homology modeling.

ResearcherID: D-1226-2012

Current research group: 2 researchers/postdocs (Dr Anna Reymer, Dr Duygu Yilmazer), 2 PhD students (Antonio Carlesso, Sonali Chavan), and several Master students, visiting researchers and PhD students.

 

TEACHING

General chemistry (KEM011)
Analytical pharmaceutical chemistry (KER210)
General pharmaceutical chemistry (KER220)
Basic Molecular Modeling (KEM552)
Lectures in various courses such as KEM350 and KMG045.  

 

COMMISSIONS OF TRUST

Vice chair of the University council for investigations of suspected misconduct in research ("Oredlighetsrådet").
Chemistry representative in C3SE board.
Spokesperson for the Division of Biochemistry and Structural Biology.

Participates in H2020 MSCA-ITN project TRAIN-ERS.
Participates in H2020 MCSA-RISE project EPIC.
Member of UGOT CARe (Center for Antibiotics Resistance Research).

 

MERITS

Leif Eriksson studied Chemistry at Stockholm university and University of Sussex 1985-1988. He received his PhD in Quantum chemistry at  Uppsala Universitet (1992), followed by a postdoctoral fellowship from the Swedish research council VR (then 'NFR') to go to Dalhousie University, Canada, 92/93. He most recently comes from NUI Galway, Ireland, and holds the current professorship in physical chemistry at GU since 2011. He was awarded the 2017 Pedagogic price from the Science section of the Göta Student Union at University of Gothenburg.

Eriksson has published >250 peer reviewed research papers and some 20 review papers and book chapters, in the field of theoretical/computational (bio)chemistry. He holds the patents of a new pharmaceutical against skin cancer and for a new inhibitor of Vitmain A degradation, and is part owner of spin-out companies Santium Pharma, C26 Bioscience, and Cell Stress Discoveries. He is currently involved in the development of several new drugs, of which the first are in the patenting stage.

Latest publications

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
Antonio Carlesso, C. Chintha, A. M. Gorman, A. Samali, Leif A Eriksson
ACS Omega, Journal article 2018
Journal article

Exploring polypharmacology in drug design
Patricia Saenz-Méndez, Leif A Eriksson
Rational drug design, Other 2018
Other

Theoretical Insights on the Inefficiency of RNA Oxidative Damage under Aerobic Conditions
S. Zhao, Leif A Eriksson, R. B. Zhang
Journal of Physical Chemistry A, Journal article 2018
Journal article

Computational Chemistry and Molecular Modelling Basics
Samuel Genheden, Anna Reymer, Patricia Saenz-Méndez, Leif A Eriksson
Computational Tools for Chemical Biology, Chapter in book 2017
Chapter in book

Homology model of the human tRNA splicing ligase RtcB
A. Nandy, Patricia Saenz-Mendez, A. M. Gorman, A. Samali, Leif A Eriksson
Proteins-Structure Function and Bioinformatics, Journal article 2017
Journal article

Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process
E. Bignon, M. Marazzi, V. Besancenot, H. Gattuso, G. Drouot et al.
Scientific Reports, Journal article 2017
Journal article

Showing 31 - 40 of 61

2014

Deamination features of 5-hydroxymethylcytosine, a radical and enzymatic DNA oxidation product
A. Grand, N. Jorge, C. Morell, J. Cadet, Leif A Eriksson
Journal of Molecular Modeling, Journal article 2014
Journal article

Rational design and validation of a Tip60 histone acetyltransferase inhibitor
Chunxia Gao, E. Bourke, M. Scobie, M. A. Famme, T. Koolmeister et al.
Scientific Reports, Journal article 2014
Journal article

2013

Modification of the anticancer drug tamoxifen to avoid CYP2D6 polymorphism
L. Gao, X. Q. Sun, Y. Q. Tu, H. Agren, Leif A Eriksson
Canadian Journal of Chemistry-Revue Canadienne De Chimie, Journal article 2013
Journal article

Showing 31 - 40 of 61

Page Manager: Katleen Burm|Last update: 9/20/2013
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