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Markus Tamas


Markus Tamas
Professor , Head of Department
molecular biology/genetics/biochemistry/yeast
+46 31 786 2548

Room number: 1450
Postal Address: Box 462, 40530 Göteborg
Visiting Address: Medicinaregatan 9 c , 41390 Göteborg

Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
Fax: +46 31 786 2599
Visiting Address: Medicinaregatan 9 C , 413 90 Göteborg

About Markus Tamas

Contact details: Lundberg Laboratory, Medicinaregatan 9, Room number 1415



Molecular biology of metal toxicity and tolerance

Many metals endanger the environment and human health, but are also increasingly used as therapeutic agents for medical treatment. Yet, little is known about the molecular mechanisms causing metal toxicity or the mechanisms by which eukaryotic cells counteract toxicity and acquire tolerance.
To gain insights into metal action and cellular tolerance mechanisms, we use front-line tools in molecular biology, biochemistry, cell biology, chemical biology and functional genomics. We study (1) transport proteins through which metals enter or leave cells, (2) signal transduction and transcriptional regulatory mechanisms that cells use to sense and respond to metals, and (3) proteins and cellular processes that are targeted by metals. We use the model eukaryote Saccharomyces cerevisiae to explore fundamental aspects of metal biology and also as a heterologous expression system to study tolerance factors from other organisms such as plants and mammals.

Publications ResearcherID: www.researcherid.com/rid/E-8183-2010

Publications Google Scholar: scholar.google.se/citations

Research team: Stefanie Weber (PhD student), Joana Rodrigues (PhD student), Sansan Hua (PhD student), Antonia Romero (postdoc)


  • Eukaryotic Molecular Microbiology (BIO440)
  • Molecular Microbiology (BIO277)
  • Cell biology (BIO900)



  • Head of Department: Department of Chemistry and Molecular Biology



Markus J. Tamás studied molecular biology and biochemistry in Lund (Sweden) and Liège (Belgium) and spent a year as a research scholar at the Public Health Research Institute in New York (USA). Markus completed his PhD at the Katholieke Universiteit Leuven (Belgium) in 1999 and then moved to Gothenburg. Markus was awarded an assistant professorship by the Swedish Research Council in 2003 and became professor in eukaryotic microbiology in 2010.

Latest publications

Editorial: Molecular Mechanisms of Metalloid Transport, Toxicity and Tolerance.
Gerd Patrick Bienert, Markus J. Tamás
Frontiers in cell and developmental biology, Editorial letter 2018
Editorial letter

Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo.
Markus J. Tamás, Bruno Fauvet, Philipp Christen, Pierre Goloubinoff
Current genetics, Review article 2018
Review article

Cadmium Causes Misfolding and Aggregation of Cytosolic Proteins in Yeast.
Therese Jacobson, Smriti Priya, Sandeep K Sharma, Stefanie Andersson, Sofia Jakobsson et al.
Molecular and Cellular Biology, Journal article 2017
Journal article

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.
Nallani Vijay Kumar, Jianbo Yang, Jitesh K Pillai, Swati Rawat, Carlos Solano et al.
Molecular and cellular biology, Journal article 2016
Journal article

Disentangling genetic and epigenetic determinants of ultrafast adaptation.
Arne B Gjuvsland, Enikö Zörgö, Jeevan Ka Samy, Simon Stenberg, Ibrahim H Demirsoy et al.
Molecular systems biology, Journal article 2016
Journal article

The mitogen-activated protein kinase Slt2 modulates arsenite transport through the aquaglyceroporin Fps1.
Doryaneh Ahmadpour, Ewa Maciaszczyk-Dziubinska, Roja Babazadeh, Sita Dahal, Magdalena Migocka et al.
FEBS letters, Journal article 2016
Journal article

HwHog1 kinase activity is crucial for survival of Hortaea werneckii in extremely hyperosmolar environments.
Anja Kejžar, Morten Grøtli, Markus J. Tamás, Ana Plemenitaš, Metka Lenassi
Fungal genetics and biology : FG & B, Journal article 2015
Journal article

Showing 41 - 50 of 76



Specificity of MAP kinase substrates – determination of consensus sequences using positional scanning peptide libraries
Jenny Veide Vilg, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás
Yeast Genetics and Molecular Biology Meeting, Toronto, Canada, Conference contribution 2008
Conference contribution

A subgroup of plant aquaporins facilitate the bi-directional diffusion of As(OH)3 and Sb(OH)3 across membranes
Gern Bienert, Michael Thorsen, Manuela Schüssler, R. Henrik Nilsson, Annemarie Wagner et al.
20th New Phytologist Symposium, Aberdeen, UK, Conference contribution 2008
Conference contribution

Role of transporters in glutathione export during arsenite exposure
Therese Jacobson, Michael Thorsen, Markus J. Tamás
International symposium on glutathione and related thiols in microorganisms and plants, Nancy, France, Conference contribution 2008
Conference contribution

Molecular control of transport systems mediating arsenite tolerance
Markus J. Tamás
SMYTE 2008, Braga, Portugal, Conference contribution 2008
Conference contribution

Characterization of the DNA-binding motif of the arsenic-responsive transcription factor Yap8p.
Yulia Ilina, Ewa Sloma, Ewa Maciaszczyk-Dziubinska, Marian Novotny, Michael Thorsen et al.
The Biochemical journal, Journal article 2008
Journal article

Glutathione export as an extracellular arsenite detoxification mechanism
Michael Thorsen, Rita Vooijs, Henk Schat, Markus J. Tamás
International symposium on glutathione and related thiols in microorganisms and plants, Nancy, France, Conference contribution 2008
Conference contribution

Modelling the yeast response to arsenite stress
Vijay Garla, Markus J. Tamás, Joerg Schaber
International Conference on Systems Biology, Gothenburg, Sweden, Conference contribution 2008
Conference contribution

Showing 41 - 50 of 76

Page Manager: Katleen Burm|Last update: 9/20/2013

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