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Leif Eriksson


Leif Eriksson
+46 31 786 9117

Postal Address: Kemigården 4, 412 96 Göteborg
Visiting Address: Kemigården 4 , 412 96 Göteborg

Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
Fax: +46 31 786 2599

Visiting Address: Medicinaregatan 9 C , 405 30 Göteborg

About Leif Eriksson

Contact information: Lundberg Lab, Medicinareg. 9c, 40530 Göteborg; office 2409.



Theoretical biophysical chemistry in form of computer based modeling of various biochemical processes and systems. Our focus has for a long time related to DNA damage processes, cancer and drug design; often linked to radical and photochemistry. In recent years, we have explored increasingly larger systems, including diffusion across biological membranes, liposomes, derivation of protein structures and studies of their mechanisms, and development of aptamers as diagnostic tool and in treatment.

We utilize a wide range of methods in our research, from DFT and QM/MM to molecular dynamics simulations and bioinformatic tools such as VHTS/docking and homology modeling.

ResearcherID: D-1226-2012

Current research group: 1 junior researcher (Dr Johan Scheers, shared with Chalmers), 1 postdoctoral fellow (Dr Samuel Genheden), 1 visiting researcher (Assoc Prof Patricia Saenz Mendez), 2 PhD students (Chunxia Gao, Min Wu).



General chemistry (KEM011)
Analytical pharmaceutical chemistry (KER210)
Physical chemistry (KEM040)
Lectures in various courses such as KEM350 and KMG045.  



Member of 3rd cycle study committee (iFUB) at CMB.
Member of the University council for investigations of suspected misconduct in research ("Oredlighetsrådet").
Chemistry representative in C3SE board.

Member for management committee of COST ACTION CM-1201, Biomimetic Radical Chemistry.
Participates in H2020 MSCA-ITN project TRAIN-ERS.
Participates in H2020 MCSA-RISE project EPIC.
Host for Assoc. Prof. Patricia Saenz-Mendez, UdelaR, Uruguay, within the framework for VGR/FP7/MSCA-programme MoRE.



Leif Eriksson studied Chemistry at Stockholm university and University of Sussex 1985-1988. He received his PhD in Quantum chemistry at  Uppsala Universitet (1992), followed by a postdoctoral fellowship from the Swedish research council VR (then 'NFR') to go to Dalhousie University, Canada, 92/93. He most recently comes from NUI Galway, Ireland, and holds the current professorship in physical chemistry at GU since 2011.

Eriksson has published ca. 250 peer reviewed research papers and some 20 review papers and book chapters, in the field of theoretical/computational (bio)chemistry. He holds the paptent of a new pharmaceutical against skin cancer, and is part owner of spin-out company Swedish Pharma. He is currently involved in the development of several new drugs, of which the first are in the patenting stage.

Latest publications

Theoretical Insights on the Inefficiency of RNA Oxidative Damage under Aerobic Conditions
S. Zhao, Leif A Eriksson, R. B. Zhang
Journal of Physical Chemistry A, Journal article 2018
Journal article

Homology model of the human tRNA splicing ligase RtcB
A. Nandy, Patricia Saenz-Mendez, A. M. Gorman, A. Samali, Leif A Eriksson
Proteins-Structure Function and Bioinformatics, Journal article 2017
Journal article

Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process
E. Bignon, M. Marazzi, V. Besancenot, H. Gattuso, G. Drouot et al.
Scientific Reports, Journal article 2017
Journal article

On the formation of a side product with hexahydroaporphine-like structure in the Grewe cyclization of dextromethorphan
Qiao Zhao, Kai Zhao, Sheng ying Wu, Bo xue Tian, Leif A Eriksson et al.
Research on Chemical Intermediates, Journal article 2017
Journal article

Targeting cancer using KAT inhibitors to mimic lethal knockouts.
James A L Brown, Emer Bourke, Leif A Eriksson, Michael J Kerin
Biochemical Society transactions, Review article 2016
Review article

Structures, Properties, and Dynamics of Intermediates in eEF2-Diphthamide Biosynthesis
Jean-Marc Billod, Patricia Saenz-Mendez, Anders Blomberg, Leif A Eriksson
Journal of Chemical Information and Modeling, Journal article 2016
Journal article

Showing 41 - 50 of 55


Antioxidant properties of beta-carotene isomers and their role in photosystems: insights from ab initio simulations
J. Cerezo, J. Zuniga, A. Bastida, A. Requena, J.P. Cerón-Carrasco et al.
Journal of Physical Chemistry A, Journal article 2012
Journal article

Comparison of the Mechanism of Deamination of 5,6-dihydro-5-methylcytosine with other cytosine derivatives
A. Grand, J. Cadet, Leif A Eriksson, V. Labet, N.L. Jorge et al.
Theoretical Chemistry accounts, Journal article 2012
Journal article

Stability and iron coordination in DNA adducts of Anthracycline based anti-cancer drugs
A. Eizaguirre, M. Yanez, Leif A Eriksson
Physical Chemistry Chemical Physics, Journal article 2012
Journal article

Cloning and Functional Studies of a Splice Variant of CYP26B1 Expressed in Vascular Cells
A. A. Elmabsout, A. Kumawat, P. Saenz-Mendez, O. Krivospitskaya, H. Savenstrand et al.
Plos One, Journal article 2012
Journal article

Characterization of Agonist Binding to His524 in the Estrogen Receptor α Ligand Binding Domain
L. Gao, Y. Tu, H. Ågren, Leif A Eriksson
Journal of Physical Chemistry B, Journal article 2012
Journal article

7-Nitro-4-(phenylthio)benzofurazan is a potent generator of superoxide and hydrogen peroxide
Erik V. Patridge, Emma S. E. Eriksson, Philip G. Penketh, Raymond P. Baumann, Rui Zhu et al.
Archives of Toxicology, Journal article 2012
Journal article

Homology models of human all-trans retinoic acid metabolizing enzymes CYP26B1 and CYP26B1 spliced-variant.
P. Saenz-Mendez, A.A. Elmabsout, H. Sävenstrand, M.K.A. Awadalla, Å. Strid et al.
Journal of Chemical Information and Modeling, Journal article 2012
Journal article

Showing 41 - 50 of 55

Page Manager: Katleen Burm|Last update: 9/20/2013

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