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Markus Tamas

Professor

Markus Tamas
Professor , Head of Department
molecular biology/genetics/biochemistry/yeast
markus.tamas@cmb.gu.se
+46 31 786 2548
0733-732548

Room number: 1450
Postal Address: Box 462, 40530 Göteborg
Visiting Address: Medicinaregatan 9 c , 41390 Göteborg


Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
www.cmb.gu.se
inst.kmb@cmb.gu.se
Fax: +46 31 786 2599
Visiting Address: Medicinaregatan 9 C , 413 90 Göteborg

About Markus Tamas

Contact details: Lundberg Laboratory, Medicinaregatan 9, Room number 1415

 

RESEARCH

Molecular biology of metal toxicity and tolerance

Many metals endanger the environment and human health, but are also increasingly used as therapeutic agents for medical treatment. Yet, little is known about the molecular mechanisms causing metal toxicity or the mechanisms by which eukaryotic cells counteract toxicity and acquire tolerance.
To gain insights into metal action and cellular tolerance mechanisms, we use front-line tools in molecular biology, biochemistry, cell biology, chemical biology and functional genomics. We study (1) transport proteins through which metals enter or leave cells, (2) signal transduction and transcriptional regulatory mechanisms that cells use to sense and respond to metals, and (3) proteins and cellular processes that are targeted by metals. We use the model eukaryote Saccharomyces cerevisiae to explore fundamental aspects of metal biology and also as a heterologous expression system to study tolerance factors from other organisms such as plants and mammals.

Publications ResearcherID: www.researcherid.com/rid/E-8183-2010

Publications Google Scholar: scholar.google.se/citations

Research team: Stefanie Weber (PhD student), Joana Rodrigues (PhD student), Sansan Hua (PhD student), Antonia Romero (postdoc)


TEACHING

  • Eukaryotic Molecular Microbiology (BIO440)
  • Molecular Microbiology (BIO277)
  • Cell biology (BIO900)

 

COMMISSIONS

  • Head of Department: Department of Chemistry and Molecular Biology

 

QUALIFICATIONS

Markus J. Tamás studied molecular biology and biochemistry in Lund (Sweden) and Liège (Belgium) and spent a year as a research scholar at the Public Health Research Institute in New York (USA). Markus completed his PhD at the Katholieke Universiteit Leuven (Belgium) in 1999 and then moved to Gothenburg. Markus was awarded an assistant professorship by the Swedish Research Council in 2003 and became professor in eukaryotic microbiology in 2010.

Latest publications

Editorial: Molecular Mechanisms of Metalloid Transport, Toxicity and Tolerance.
Gerd Patrick Bienert, Markus J. Tamás
Frontiers in cell and developmental biology, Editorial letter 2018
Editorial letter

Misfolding and aggregation of nascent proteins: a novel mode of toxic cadmium action in vivo.
Markus J. Tamás, Bruno Fauvet, Philipp Christen, Pierre Goloubinoff
Current genetics, Review article 2018
Review article

Cadmium Causes Misfolding and Aggregation of Cytosolic Proteins in Yeast.
Therese Jacobson, Smriti Priya, Sandeep K Sharma, Stefanie Andersson, Sofia Jakobsson et al.
Molecular and Cellular Biology, Journal article 2017
Journal article

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.
Nallani Vijay Kumar, Jianbo Yang, Jitesh K Pillai, Swati Rawat, Carlos Solano et al.
Molecular and cellular biology, Journal article 2016
Journal article

Disentangling genetic and epigenetic determinants of ultrafast adaptation.
Arne B Gjuvsland, Enikö Zörgö, Jeevan Ka Samy, Simon Stenberg, Ibrahim H Demirsoy et al.
Molecular systems biology, Journal article 2016
Journal article

The mitogen-activated protein kinase Slt2 modulates arsenite transport through the aquaglyceroporin Fps1.
Doryaneh Ahmadpour, Ewa Maciaszczyk-Dziubinska, Roja Babazadeh, Sita Dahal, Magdalena Migocka et al.
FEBS letters, Journal article 2016
Journal article

HwHog1 kinase activity is crucial for survival of Hortaea werneckii in extremely hyperosmolar environments.
Anja Kejžar, Morten Grøtli, Markus J. Tamás, Ana Plemenitaš, Metka Lenassi
Fungal genetics and biology : FG & B, Journal article 2015
Journal article

Showing 51 - 60 of 76

2007

Quantitative transcriptome, proteome and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite
Michael Thorsen, Gilles Lagniel, Erik Kristiansson, Christophe Junot, Olle Nerman et al.
Gordon Research Conference on Metals in Biology, Newport, USA, Conference contribution 2007
Conference contribution

Membrane transport of arsenite and other uncharged metalloids through aquaporins of Arabidopsis thaliana
Gern Bienert, Markus J. Tamás, Manuela Schüssler, Thomas Jahn
International conference on aquaporins, Nara, Japan, Conference contribution 2007
Conference contribution

2006

The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.
Michael Thorsen, Yujun Di, Carolina Tängemo, Montserrat Morillas, Doryaneh Ahmadpour et al.
Molecular biology of the cell, Journal article 2006
Journal article

The MAP kinase Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast
Michael Thorsen, Yujun Di, Carolina Tängemo, Montserrat Morillas, Francesc Posas et al.
Yeast Genetics and Molecular Biology Meeting, Princeton, USA, Conference contribution 2006
Conference contribution

Activity of the arsenic-responsive transcription factor Yap8p is controlled by the ubiquitin-proteasome pathway
Yujun Di, Markus J. Tamás
Yeast Genetics and Molecular Biology Meeting, Princeton, USA, Conference contribution 2006
Conference contribution

2005

Mechanisms of toxic metal tolerance in yeast
Markus J. Tamás, Jean Labarre, Michel B. Toledano, Robert Wysocki
Molecular Biology of Metal Homeostasis and Detoxification; Eds Tamás M.J and Martinoia E., Chapter in book 2005
Chapter in book

Arsenic-activation of the yeast AP-1-like transcription factors Yap1p and Yap8p
Yujun Di, Markus J. Tamás
Yeast, Conference contribution 2005
Conference contribution

The cellular response to arsenic exposure
Markus J. Tamás, Michael Thorsen, Jean Labarre
Yeast, Conference contribution 2005
Conference contribution

Showing 51 - 60 of 76

Page Manager: Katleen Burm|Last update: 9/20/2013
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