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Leif Eriksson

Professor

Leif Eriksson
Professor
leif.eriksson@chem.gu.se
+46 31 786 9117
0766-229117

Room number: 1405
Postal Address: Box 462, 40530 Göteborg
Visiting Address: Medicinaregatan 9c, Lundberg Lab, , 41390 Göteborg


Department of Chemistry & Molecular Biology (More Information)
Box 462
405 30 Göteborg
www.cmb.gu.se
inst.kmb@cmb.gu.se
Fax: +46 31 786 2599
Visiting Address: Medicinaregatan 9 C , 413 90 Göteborg

About Leif Eriksson

Contact information: Lundberg Lab, Medicinareg. 9c, 40530 Göteborg; office 1405.

 

 RESEARCH

Theoretical biophysical chemistry in form of computer based modeling of various biochemical processes and systems. Our focus has for a long time related to DNA damage processes, cancer and drug design; often linked to radical and photochemistry. In recent years, we have explored increasingly larger systems, including diffusion across biological membranes, drug loaded liposomes, derivation of protein structures and studies of their mechanisms, modeling of protein-protein complexes, and development of new inhibitors in cancer treatment and as antibiotics. 

We utilize a wide range of methods in our research, from DFT and QM/MM to molecular dynamics simulations and bioinformatic tools such as VHTS/docking and homology modeling.

ResearcherID: D-1226-2012

Current research group: 1 researcher (Dr Anna Reymer), 3 PhD students (Antonio Carlesso, Sonali Chavan, Johanna Hörberg), and several Master students, visiting researchers and PhD students.

 

TEACHING

General chemistry (KEM011)
Analytical pharmaceutical chemistry (KER210)
General pharmaceutical chemistry (KER220)
Basic Molecular Modeling (KEM552)
Lectures in various courses such as KEM350 and KMG045.  

 

COMMISSIONS OF TRUST

Vice head of department for research.
Chemistry representative in C3SE board.
Spokesperson for the Division of Biochemistry and Structural Biology.

Participates in H2020 MSCA-ITN project TRAIN-ERS.
Participates in H2020 MCSA-RISE project EPIC.
Member of UGOT CARe (Center for Antibiotics Resistance Research).

 

MERITS

Leif Eriksson studied Chemistry at Stockholm university and University of Sussex 1985-1988. He received his PhD in Quantum chemistry at  Uppsala Universitet (1992), followed by a postdoctoral fellowship from the Swedish research council VR (then 'NFR') to go to Dalhousie University, Canada, 92/93. He most recently comes from NUI Galway, Ireland, and holds the current professorship in physical chemistry at GU since 2011. He was awarded the 2017 Pedagogic price from the Science section of the Göta Student Union at University of Gothenburg.

Eriksson has published >250 peer reviewed research papers and some 20 review papers and book chapters, in the field of theoretical/computational (bio)chemistry. He holds the patents of a new pharmaceutical against skin cancer and for a new inhibitor of Vitmain A degradation, and is part owner of spin-out companies Santium Pharma, C26 Bioscience, and Cell Stress Discoveries. He is currently involved in the development of several new drugs, of which the first are in the patenting stage.

Latest publications

A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation
A. Tashakor, M. H-Dehkordi, E. O'Connell, S. G. Ganau, R. Gozalbes et al.
Febs Open Bio, Journal article 2019
Journal article

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation
M. Maurel, J. Obacz, T. Avril, Y. P. Ding, O. Papadodima et al.
EMBO Molecular Medicine, Journal article 2019
Journal article

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors
M. Mahameed, T. Wilhelm, O. Darawshi, A. Obiedat, W. S. Tommy et al.
Cell Death and Disease, Journal article 2019
Journal article

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications
A. Almanza, Antonio Carlesso, C. Chintha, S. Creedican, D. Doultsinos et al.
Febs Journal, Journal article 2019
Journal article

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
Antonio Carlesso, C. Chintha, A. M. Gorman, A. Samali, Leif A Eriksson
ACS Omega, Journal article 2018
Journal article

Exploring polypharmacology in drug design
Patricia Saenz-Méndez, Leif A Eriksson
Rational drug design, Other 2018
Other

Showing 31 - 40 of 68

2015

Membrane engineering for reduced acetic acid stress: insights from Zygosaccharomyces bailii
Lina Lindahl, Aline X S Santos, Samuel Genheden, Leif A Eriksson, Howard Riezman et al.
Oral presentation at 12th Yeast Lipid Conference, May 20-22 2015, Ghent, Belgium, Conference contribution 2015
Conference contribution

Membrane engineering for reduced acetic acid stress: insights from Zygosaccharomyces bailii
Lina Lindahl, Samuel Genheden, Leif A Eriksson, Lisbeth Olsson, Maurizio Bettiga
Oral presentation at 37th Symposium on Biotechnology for Fuels and Chemicals (SBFC), April 27-30 2015, San Diego, USA, Conference contribution 2015
Conference contribution

2014

THE INFLUENCE OF MEMBRANE COMPOSTION ON ACETIC ACID PERMEABILITY AND POTENTIALLY ACETIC ACID TOLERANCE
Lina Lindahl, Helén Olsson, Samuel Genheden, Leif A Eriksson, Aline X S Santos et al.
ISSY31: 31st International Specialised Symposium on Yeast, Other 2014
Other

Improved homology model of cyclohexanone monooxygenase from Acinetobacter calcoaceticus based on multiple templates
Eduardo Bermúdez, Oscar N. Ventura, Leif A Eriksson, Patricia Saenz-Méndez
Computational biology and chemistry, Journal article 2014
Journal article

Deamination features of 5-hydroxymethylcytosine, a radical and enzymatic DNA oxidation product
A. Grand, N. Jorge, C. Morell, J. Cadet, Leif A Eriksson
Journal of Molecular Modeling, Journal article 2014
Journal article

Showing 31 - 40 of 68

Page Manager: Katleen Burm|Last update: 9/20/2013
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