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Molecular and Cellular Biology

The Division of Molecular and Cellular Biology studies molecules and cells, and delivers fundamental research to improve environmental and human health.

Key target areas are

  • pollution
  • cancer
  • aging
  • infections
  • metabolic, developmental and neurodegenerative diseases and disorders.

Our researchers combine genetic and molecular tools, such as genetic engineering and screening, with computational approaches to understand yeast, bacterial, worm, mouse and human cells. A particular strength is the use of yeast as an advanced cell model and access to automated high throughput platforms for mega science.

Key research areas are

  • Antibiotic resistance
  • Cytoskeletal dynamics
  • Embryonic developmentMetal biology
  • Microbial signalling and communities
  • Molecular evolution
  • Protein quality control
  • Regulation of metabolism
  • Stress resistance.

The Division of Molecular and Cellular Biology is at the heart of life sciences at University of Gothenburg and has fruitful interdisciplinary interactions with chemists, bioinformaticians, clinicians and biomedical companies. The division entertains many long term national and international collaborations.

Research papers published in top-rated scientific journals and prestigious personal grants from the most renowned funding agencies including the European Reserach Council (ERC) reflect our scientific excellence.

The division provides a warm, welcoming and collaborative  environment for cell and molecular research and an outstanding training platform for students and young scientists.

Research groups within the division of Molecular and Cellular Biology

Anders BlombergAnders Blomberg

Studies how in particular marine organisms handle stress, drugs and polluting chemicals. Models: yeast, barnacle.

 

Peter Carlsson

Studies how a class of regulatory proteins control gene expression in embryonic development, cellular differentiation and disease using mouse genetics and in vitro methods. Models: mouse, human cells.

Anne FarewellAnne Farewell

Studying how antibiotic resistance genes spread between bacteria and aims to develop ways to prevent this. This will extend the usefulness of our antibiotics. Also works to improve science teaching. Models: bacteria.

Julie Grantham

The molecular chaperone CCT and the cytoskeleton: understanding the interplay between the folding of actin and tubulin by the CCT oligomer and the role of CCT in modulated processes involving assembled microtubules and actin filaments. Models: human cells.

Malte HermanssonMalte Hermansson

Bacteria clean our wastewater; research on biofilm ecology can make nitrogen removal more efficient. Is bacterial adhesion regulated by cell surface structures and can fimbriae act as sensors for surface properties? Models: bacteria.

Beidong Liu

Developing and applying yeast (Saccharomyces cerevisiae) high throughput phenomic screening approaches for deciphering mechanisms underlying how protein aggregates influence cellular ageing and stress response. Models: yeast.

Margit MahlapuuMargit Mahlapuu

The main focus is to elucidate the molecular mechanisms regulating lipid partitioning, inflammatory infiltration and insulin sensitivity in the liver, and cross-talk between the liver and other peripheral tissues prone to lipotoxicity. Models: mouse, human cells.

Marc PilonMarc Pilon

Genetic mechanisms that regulate cell membrane composition in response to dietary or environmental challenges. Models: worm, mouse and human cells.

 

Hiroki Shibuya

Study of chromosome dynamics during mammalian meiosis using a combination of approaches in genetics, cytology and biochemistry. Models: mouse, human cells.

Per SunnerhagenPer Sunnerhagen

Adaptation to stress changes expression and localization of RNA, and may cause stress granules to form. These in turn affect gene expression and cell signaling. In cancer cells, they may change the response to therapy.
Antimicrobial resistance in bacteria and Plasmodium is a threat to treatment of infectious diseases. Novel antimicrobial molecules with novel mechanisms of action are sought. Models: yeast, bacteria.

Markus TamasMarkus Tamas

Molecular and cellular biology of metal toxicity and tolerance. Front-line tools in molecular biology, biochemistry, microbiology and functional genomics are used to gain insights into metal action and cellular tolerance mechanisms. Models: yeast.

Jonas Warringer

Molecules in tumorous and infectious cells change over time often causing treatments to fail. Understanding and addressing molecular evolution may reduce treatment resistance in cells and improve human health. Models: yeast, bacteria.

Research for sustainable development

The 17 Sustainable Development Goals.Our research in Molecular and Cellular Biology contributes to sustainable development in many different ways. Amongst others, we work with:

Health and Well-Being.

The division seeks to discover new targets and strategies for addressing:

• Cancer
• Aging
• Malaria
• Bacterial infections and antibiotics resistance
• Neurodegenerative diseases, including Alzheimer
• Developmental diseases
• Metabolic diseases, including Diabetes, and fatty liver
• Heritable

Clean water and sanitation as well as Sustainable cities and communities.
The division develops new strategies for addressing

• Metal and chemical pollution in land and sea
• Waste water treatmen

Read more about Research and Sustainable Development

The Department's Principal Investigators

The Department's scientific publications

Page Manager: Katleen Burm|Last update: 11/7/2019
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