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Experimental skin research

The research methodology we are using can be applied for experimental skin research. For example we investigate how MPM can be applied for diagnostics of skin cancer, how fluorescent model compounds diffuse and penetrate into the skin, or how reactive substances form hapten-protein complexes. For more information, see the following publications:

  • Kantere, D. et al. Anti-Stokes fluorescence from endogenously formed protoporphyrin IX - Implications for clinical multiphoton diagnostics. Journal of Biophotonics 6, 409-415 (2013).
  • Simonsson, C., Stenfeldt, A. L., Karlberg, A. T., Ericson, M. B. & Jonsson, C. A. M. The pilosebaceous unit-a phthalate-induced pathway to skin sensitization. Toxicology and Applied Pharmacology 264, 114-120 (2012).
  • Simonsson, C. et al. Caged Fluorescent Haptens Reveal the Generation of Cryptic Epitopes in Allergic Contact Dermatitis. Journal of Investigative Dermatology 131, 1486-1493 (2011).
  • Samuelsson, K. et al. Accumulation of FITC near stratum corneum-visualizing epidermal distribution of a strong sensitizer using two-photon microscopy. Contact Dermatitis 61, 91-100 (2009).
  • Paoli, J., Smedh, M., Wennberg, A. M. & Ericson, M. B. Multiphoton Laser Scanning Microscopy on Non-Melanoma Skin Cancer: Morphologic Features for Future Non-Invasive Diagnostics. J. Inv. Derm. 128, 1248-55 (2008).

 

 

/2017-09-18

Page Manager: Katleen Burm|Last update: 1/7/2019
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Denna text är utskriven från följande webbsida:
http://cmb.gu.se/english/research/organic-and-medicinal-chemistry/Biomedical_Photonics/projects/experimental-skin-research/
Utskriftsdatum: 2019-07-16