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- John Fletcher
John Fletcher
Professor
Institutionen för kemi ochOm John Fletcher
Min forskning är fokuserad på utveckling och tillämpning av avbildande masspektrometri, särskilt för biologisk analys. Time-of-flight sekundär jon masspektrometri (ToF-SIMS) använder en fokuserad jonstråle för att frigöra atomer och molekyler från en yta. Dessa analyseras sedan med masspektrometri. Genom att flytta jonstrålen från pixel till pixel genereras en kemisk karta över provets yta. Tekniken tillåter nu kemisk specifik avbildning på en sub-cellulär nivå utan behov av markörer. I och med implementeringen av polyatomära jonkällor som C60 och på senare tid gasklusterjonstrålar erbjuds nu en väg till molekylärdjupprofilering (övervakning av kemiska signaler när provet långsamt urholkas av jonstrålen) och 3D molekylär avbildning.
Det finns en naturlig komplementaritet mellan ToF-SIMS och matris assisterad laser desorption jonisering (MALDI) avbildning och jag använder en kombination av dessa tekniker för att undersöka biologiska processer på en cellulär nivå.
Gruppmedlemmar:
Alfred Fransson
Simon Uzoni
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Correlative Cellular Mass Spectrometry Imaging and Amperometry Show Dose Dependent Changes in Lipid Composition and
Exocytosis
Inci Barut, Xiulan He, Erol Sener, Sanna Sämfors, Andrew G Ewing, John S. Fletcher
Angewandte Chemie - International Edition - 2023 -
SIMS and electrochemistry correlate dose dependent alterations on
cells
Inci Barut, Xiulan He, Erol Sener, Sanna Sämfors, Andrew G Ewing, John S. Fletcher
Annual Conference on Mass Spectrometry Imaging and Integrated Topics - 2023 -
Cell and tissue imaging by secondary ion mass
spectrometry
Inci Barut, John S. Fletcher
Biointerphases - 2023 -
(CO2)n+, (H2O)n+, and (H2O)n+ (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer’s model mouse brain
tissue
Kelly Dimovska Nilsson, Anthi Karagianni, Ibrahim Kaya, Marcus Henricsson, John S. Fletcher
Analytical and Bioanalytical Chemistry - 2021 -
Correlated fluorescence microscopy and multi-ion beam secondary ion mass spectrometry imaging reveals phosphatidylethanolamine increases in the membrane of cancer cells over-expressing the molecular chaperone subunit CCT
delta
John S. Fletcher, Sanna Sämfors, Josefine Vallin, Andreas Svanström, Julie Grantham
Analytical and Bioanalytical Chemistry - 2021 -
Interrogation of chemical changes on, and through, the bacterial envelope of Escherichia coli FabF mutant using time-of-flight secondary ion mass
spectrometry
Kelly Dimovska Nilsson, Johan Grandén, Anne Farewell, John S. Fletcher
Surface and Interface Analysis - 2021 -
Lipid Diversity in Cells and Tissue Using Imaging
SIMS
Sanna Sämfors, John S. Fletcher
Annual Review of Analytical Chemistry - 2020 -
Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimer's disease
mice
Ibrahim Kaya, Eva Jennische, Stefan Lange, A. T. Baykal, P. Malmberg, John S. Fletcher
Journal of Neurochemistry - 2020 -
TOF-SIMS imaging reveals tumor heterogeneity and inflammatory response markers in the microenvironment of basal cell
carcinoma
Kelly Dimovska Nilsson, Noora Neittaanmäki, Oscar Zaar, Tina B. Angerer, John Paoli, John S. Fletcher
Biointerphases - 2020 -
Mass Spectrometry Imaging of Cocaine, Drug Removal and Methylphenidate AlterPhospholipids in Drosophila
Brain
Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Biorxiv preprint - 2020 -
Spatial Lipidomics Reveals Region and Long Chain Base Specific Accumulations of Monosialogangliosides in Amyloid Plaques in Familial Alzheimer's Disease Mice (5xFAD)
Brain.
Ibrahim Kaya, Eva Jennische, Johan Dunevall, Stefan Lange, Andrew G Ewing, Per Malmberg, Ahmet Tarik Baykal, John S. Fletcher
ACS chemical neuroscience - 2020 -
Multimodal MALDI Imaging Mass Spectrometry Reveals Spatially Correlated Lipid and Protein Changes in Mouse Heart with Acute Myocardial
Infarction
Ibrahim Kaya, Sanna Sämfors, Malin Levin, Jan Borén, John S. Fletcher
Journal of the American Society for Mass Spectrometry - 2020 -
Interplay between Cocaine, Drug Removal, and Methylphenidate Reversal on Phospholipid Alterations in Drosophila Brain Determined by Imaging Mass
Spectrometry
Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
ACS Chemical Neuroscience - 2020 -
Chemical Changes On, and Through, The Bacterial Envelope in Escherichia coli Mutants Exhibiting Impaired Plasmid Transfer Identified Using Time-of-Flight Secondary Ion Mass
Spectrometry.
Kelly Dimovska Nilsson, Martin Palm, James Hood, Jake Sheriff, Anne Farewell, John S. Fletcher
Analytical chemistry - 2019 -
Localised lipid accumulation detected in infarcted mouse heart tissue using
ToF-SIMS
S. Samfors, Marcus Ståhlman, Martina Klevstig, Jan Borén, John S. Fletcher
International Journal of Mass Spectrometry - 2019 -
Chemical imaging of aggressive basal cell carcinoma using time-of-flight secondary ion mass
spectrometry.
Marwa Munem, Oscar Zaar, Kelly Dimovska Nilsson, Noora Neittaanmäki, John Paoli, John S. Fletcher
Biointerphases - 2018 -
Benefits of NaCl addition for time-of-flight secondary ion mass spectrometry analysis including the discrimination of diacylglyceride and triacylglyceride
ions
S. Samfors, Andrew G Ewing, John S. Fletcher
Rapid Communications in Mass Spectrometry - 2018 -
On-Tissue Chemical Derivatization of Catecholamines Using 4-(N-Methyl)pyridinium Boronic Acid for ToF-SIMS and LDI-ToF Mass Spectrometry
Imaging
Ibrahim Kaya, S. M. Brülls, Johan Dunevall, Eva Jennische, Stefan Lange, J. Martensson, Andrew G Ewing, Per Malmberg, John S. Fletcher
Analytical Chemistry - 2018 -
Mass Spectrometry Imaging Shows Cocaine and Methylphenidate Have Opposite Effects on Major Lipids in Drosophila
Brain
Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Per Malmberg, Andrew G Ewing
Acs Chemical Neuroscience - 2018 -
Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological
Tissues
T. P. Siegel, G. Hamm, J. Bunch, J. Cappell, John S. Fletcher, K. Schwamborn
Molecular Imaging and Biology - 2018 -
Lipid Heterogeneity Resulting from Fatty Acid Processing in the Human Breast Cancer Microenvironment Identified by GCIB-ToF-SIMS
Imaging
Tina B. Angerer, Ylva Magnusson, Göran Landberg, John S. Fletcher
Analytical Chemistry - 2016 -
Evaluation of biomolecular distributions in rat brain tissues by means of ToF-SIMS using a continuous beam of Ar
clusters
Shusuke Nakano, Yuta Yokoyama, Satoka Aoyagi, Naoyuki Himi, John S. Fletcher, Nicholas P. Lockyer, Alex Henderson, John C. Vickerman
Biointerphases - 2016 -
Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass
spectrometry
Amir Saeid Mohammadi, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Analytical and Bioanalytical Chemistry - 2016 -
Multimodal Imaging of Chemically Fixed Cells in Preparation for
NanoSIMS
Jelena Lovric, Per Malmberg, Bengt R Johansson, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2016 -
Cholesterol Alters the Dynamics of Release in Protein Independent Cell Models for
Exocytosis
Neda Najafinobar, Lisa J. Mellander, Michael E. Kurczy, Johan Dunevall, Tina B. Angerer, John S. Fletcher, Ann-Sofie Cans
Scientific Reports - 2016 -
Investigating the Role of the Stringent Response in Lipid Modifications during the Stationary Phase in E. coli by Direct Analysis with Time-of-Flight-Secondary Ion Mass
Spectrometry
Patrick M. Wehrli, Tina B. Angerer, Anne Farewell, John S. Fletcher, Johan Gottfries
Analytical Chemistry - 2016 -
Optimizing sample preparation for anatomical determination in the hippocampus of rodent brain by ToF-SIMS
analysis
Tina B. Angerer, Amir Saeid Mohammadi, John S. Fletcher
Biointerphases - 2016 -
Peptide Fragmentation and Surface Structural Analysis by Means of ToF-SIMS Using Large Cluster Ion
Sources
Y. Yokoyama, S. Aoyagi, M. Fujii, J. Matsuo, John S. Fletcher, N. P. Lockyer, J. C. Vickerman, M. K. Passarelli, R. Havelund, M. P. Seah
Analytical Chemistry - 2016 -
Lipid Structural Effects of Oral Administration of Methylphenidate in Drosophila Brain by Secondary Ion Mass Spectrometry
Imaging
Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2015 -
Comparing depth profiling of oxide scale on SOFC interconnect-materials using ToF-SIMS with Ga-69(+), Bi-3(+)/Cs+ and C-60(+)/C-60(2+) as primary and sputter
ions
Josefin Hall, U. Bexell, John S. Fletcher, Sead Canovic, Per Malmberg
Materials at High Temperatures - 2015 -
Improved Molecular Imaging in Rodent Brain with Time-of-Flight-Secondary Ion Mass Spectrometry Using Gas Cluster Ion Beams and Reactive Vapor
Exposure
Tina B. Angerer, Masoumeh Dowlatshahi Pour, Per Malmberg, John S. Fletcher
Analytical Chemistry - 2015 -
Significant Enhancement of Negative Secondary Ion Yields by Cluster Ion Bombardment Combined with Cesium
Flooding
P. Philipp, Tina B. Angerer, Sanna Sämfors, P. Blenkinsopp, John S. Fletcher, T. Wirtz
Analytical Chemistry - 2015 -
3D imaging of biological specimen using
MS
John S. Fletcher
Bioanalysis - 2015 -
Measuring Compositions in Organic Depth Profiling: Results from a VAMAS Interlaboratory
Study
A. G. Shard, R. Havelund, S. J. Spencer, I. S. Gilmore, M. R. Alexander, Tina B. Angerer, S. Aoyagi, J. P. Barnes, A. Benayad, A. Bernasik, G. Ceccone, J. D. P. Counsell, C. Deeks, John S. Fletcher, D. J. Graham, C. Heuser, T. G. Lee, C. Marie, M. M. Marzec, G. Mishra, D. Rading, O. Renault, D. J. Scurr, H. K. Shon, V. Spampinato, H. Tian, F. Y. Wang, N. Winograd, K. Wu, A. Wucher, Y. F. Zhou, Z. H. Zhu
Journal of Physical Chemistry B - 2015 -
Latest applications of 3D ToF-SIMS
bio-imaging
John S. Fletcher
Biointerphases - 2015 -
High energy gas cluster ions for organic and biological analysis by time-of-flight secondary ion mass
spectrometry
Tina B. Angerer, Paul Blenkinsopp, John S. Fletcher
International Journal of Mass Spectrometry - 2015 -
Imaging Mass Spectrometry for Single-Cell
Analysis
Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering - 2014 -
Spatiotemporal lipid profiling during early embryo development of Xenopus laevis using dynamic Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS)
Imaging
Hua Tian, John S. Fletcher, Raphael Thuret, Alex Henderson, Nancy Papalopulu, John Vickerman, Nicholas Lockyer
Journal of Lipid Research - 2014 -
ToF-SIMS imaging of lipids and lipid related compounds in Drosophila
brain
Nhu TN Phan, John S. Fletcher, Peter Sjövall, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014 -
Analysis of liposome model systems by time-of-flight secondary ion mass
spectrometry
Jelena Lovric, Jacqueline Keighron, Tina B. Angerer, Xianchan Li, Per Malmberg, John S. Fletcher, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014 -
Gold and silver nanoparticle-assisted laser desorption ionization mass spectrometry compatible with secondary ion mass spectrometry for lipid
analysis
Amir Saeid Mohammadi, John S. Fletcher, Per Malmberg, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014 -
Maximising the potential for bacterial phenotyping using time‐of‐flight secondary ion mass spectrometry with multivariate analysis and Tandem Mass
Spectrometry
Patrick M. Wehrli, Erika Lindberg, Tina B. Angerer, Agnes E Wold, Johan Gottfries, John S. Fletcher
Surface and Interface Analysis - 2014 -
Prospect of increasing secondary ion yields in ToF-SIMS using water cluster primary ion
beams
S. Sheraz, A. Barber, I. B. Razo, John S. Fletcher, N. P. Lockyer, J. C. Vickerman
Surface and Interface Analysis - 2014 -
3D Imaging of TiO2 nanoparticle accumulation in tetrahymena
pyriformis
Tina B. Angerer, John S. Fletcher
Surface and Interface Analysis - 2014 -
Examination of fragment ions of polystyrene in TOF-SIMS spectra using
MS/MS
T. Kawashima, T. Kurosawa, S. Aoyagi, S. Sheraz, John S. Fletcher, M. Futigami, N. P. Lockyer, J. C. Vickerman
Surface and Interface Analysis - 2014 -
Time-of-Flight Secondary Ion Mass Spectrometry Based Molecular Histology of Human Spinal Cord Tissue and Motor
Neurons
Jörg Hanrieder, Per Malmberg, Olle R Lindberg, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2013 -
Compositional characterisation of metallurgical grade silicon and porous silicon nanosponge
particles
Edward G. Chadwick, N. V. V. Mogili, Colm O'Dwyer, Jimmy D. Moore, John S. Fletcher, Fathima Laffir, Gordon Armstrong, David A. Tanner
RSC Advances - 2013 -
Cluster and polyatomic primary ion
beams
John S. Fletcher, Christopher Szakal
ToF-SIMS: Materials Analysis by Mass Spectrometry, 2nd Ed. - 2013 -
Peptide structural analysis using continuous Ar cluster and C60 ion
beams
Satoka Aoyagi, John S. Fletcher, Sadia Sheraz, Tomoko Kawashima, Irma Berrueta Razo, Alex Henderson, Nicholas P Lockyer, John C Vickerman
Analytical and Bioanalytical Chemistry - 2013 -
Enhancing Secondary Ion Yields in Time of Flight-Secondary Ion Mass Spectrometry Using Water Cluster Primary
Beams
Sadia Sheraz, Andrew Barber, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Analytical Chemistry - 2013 -
Evaluating the challenges associated with time-of-fight secondary ion mass spectrometry for metabolomics using pure and mixed
metabolites
John S. Fletcher, Helen L Kotze, Emily G. Armitage, Nicholas P Lockyer, John C. Vickerman
Metabolomics - 2013 -
ToF-SIMS as a tool for metabolic profiling small biomolecules in cancer
systems
Helen L. Kotze, Emily G. Armitage, John S. Fletcher, Alex Henderson, Kaye J. Williams, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis - 2013 -
Time-of-flight SIMS as a novel approach to unlocking the hypoxic properties of
cancer
Emily G Armitage, Helen L Kotze, John S. Fletcher, Kaye J Williams, Nicholas P. Lockyer, John C Vickerman
Surface and Interface Analysis - 2013 -
Peak picking as a pre-processing technique for imaging time of flight secondary ion mass
spectrometry
Jimmy D. Moore, Alex Henderson, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis - 2013 -
Comparison of C60 and GCIB primary ion beams for the analysis of cancer cells and tumour
sections
John S. Fletcher, Sadia Rabbani, Andrew M. Barber, Nicholas P. Locker, John C. Vickerman
Surface and Interface Analysis - 2013 -
Secondary Ion Mass Spectrometry: Characterizing Complex Samples in Two and Three
Dimensions.
John S. Fletcher, John C Vickerman
Analytical chemistry - 2013 -
The inherent problem of transflection-mode infrared spectroscopic microscopy and the ramifications for biomedical single point and imaging
applications.
Paul Bassan, Joe Lee, Ashwin Sachdeva, Juliana Pissardini, Konrad M Dorling, John S. Fletcher, Alex Henderson, Peter Gardner
The Analyst - 2013 -
A Comparative Study of Secondary Ion Emission from Water Ice under Ion Bombardment by Au(+), Au(3)(+), and
C(60)(+)
Xavier A Conlan, John S. Fletcher, Nicholas P Lockyer, John C Vickerman
Journal of Physical Chemistry C - 2012 -
Molecular SIMS imaging; spatial resolution and molecular sensitivity: Have we reached the end of the road? Is there light at the end of the
tunnel?
John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis - 2011 -
TOF-SIMS with Argon Gas Cluster Ion Beams: A Comparison with
C(60)(+)
Sadia Rabbani, Andrew M. Barber, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Analytical Chemistry - 2011 -
Three-dimensional mass spectral imaging of HeLa-M cells - sample preparation, data interpretation and
visualisation
John S. Fletcher, Sadia Rabbani, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Rapid Communications in Mass Spectrometry - 2011 -
A new time-of-flight SIMS instrument for 3D imaging and
analysis
Rowland Hill, Paul Blenkinsopp, Stephen Thompson, John Vickerman, John S. Fletcher
Surface and Interface Analysis - 2011 -
Developments in molecular SIMS depth profiling and 3D imaging of biological systems using polyatomic primary
ions
John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Mass Spectrometry Reviews - 2011 -
Exploring subcellular imaging on the buncher-ToF J105 3D chemical
imager
S. Rabbani, John S. Fletcher, N. P. Lockyer, J. C. Vickerman
Surface and Interface Analysis - 2011 -
Top-down approach to studying biological components using
ToF-SIMS
Alan M. Piwowar, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis - 2011 -
Investigating the effect of temperature on depth profiles of biological material using
ToF‐SIMS
Alan M. Piwowar, John S. Fletcher, Nicholas Lockyer, John Vickerman
Surface and Interface Analysis - 2011 -
Label free biochemical 2D and 3D imaging using secondary ion mass
spectrometry.
John S. Fletcher, John C Vickerman, Nicholas Winograd
Current opinion in chemical biology - 2011 -
2 and 3D TOF-SIMS Imaging for Biological
Analysis
John S. Fletcher
Detection of Biological Agents For the Prevention of Bioterrorism - 2010 -
A new SIMS paradigm for 2D and 3D molecular imaging of
bio-systems
John S. Fletcher, John C. Vickerman
Analytical and Bioanalytical Chemistry - 2010 -
Effects of Cryogenic Sample Analysis on Molecular Depth Profiles with TOF-Secondary Ion Mass
Spectrometry
Alan M. Piwowar, John S. Fletcher, Jeanette Kordys, Nicholas P. Lockyer, Nicholas Winograd, John C. Vickerman
Analytical Chemistry - 2010 -
Time of Flight Mass Spectrometry Imaging of Samples Fractured In Situ with a Spring-Loaded Trap
System.
Ingela Lanekoff, Michael E. Kurczy, Rowland Hill, John S. Fletcher, John C Vickerman, Nick Winograd, Peter Sjövall, Andrew G Ewing
Analytical chemistry - 2010 -
Explanatory multivariate analysis of ToF-SIMS spectra for the discrimination of bacterial
isolates
Seetharaman Vaidyanathan, John S. Fletcher, Roger M. Jarvis, Alex Henderson, Nicholas P. Lockyer, Royston Goodacre, John C. Vickerman
Analyst - 2009 -
A comparison of PCA and MAF for ToF-SIMS image
interpretation
Alex Henderson, John S. Fletcher, John C. Vickerman
Surface and Interface Analysis - 2009 -
Cellular imaging with secondary ion mass
spectrometry
John S. Fletcher
Analyst - 2009 -
A Comparative Study of Secondary Ion Emission from Water Ice under Ion Bombardment by Au+, Au3+, and
C60+
Conlan Xavier, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Journal of Physical Chemistry C - 2009 -
A New Dynamic in Mass Spectral Imaging of Single Biological
Cells
John S. Fletcher, Sadia Rabbani, Alex Henderson, Paul Blenkinsopp, Steve P. Thompson, Nicholas P. Lockyer, John C. Vickerman
Analytical Chemistry - 2008 -
Uncovering new challenges in bio-analysis with
ToF-SIMS
John S. Fletcher, Alex Henderson, Gregory X. Biddulph, Seetharaman Vaidyanathan, Nicholas P. Lockyer, John C. Vickerman
Applied Surface Science - 2008 -
Exploratory analysis of TOF-SIMS data from biological
surfaces
Seetharaman Vaidyanathan, John S. Fletcher, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Applied Surface Science - 2008 -
TOF-SIMS investigation of Streptomyces coelicolor, a mycelial
bacterium
Seetharaman Vaidyanathan, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Applied Surface Science - 2008 -
Substrate effects on the analysis of biomolecular layers using Au+, Au3+ and C60+
bombardments
Jeanette Kordys, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Applied Surface Science - 2008 -
Subsurface Biomolecular Imaging of Streptomyces coelicolor Using Secondary Ion Mass
Spectrometry
Seetharaman Vaidyanathan, John S. Fletcher, Roy Goodacre, Nicholas P. Lockyer, Jason Micklefield, John C. Vickerman
Analytical Chemistry - 2008 -
Properties of C-84 and C24H12 molecular ion sources for routine TOF-SIMS
analysis
Gregory X. Biddulph, Alan M. Piwowar, John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Analytical Chemistry - 2007 -
TOF-SIMS 3D biomolecular imaging of Xenopus laevis oocytes using buckminsterfullerene (C-60) primary
ions
John S. Fletcher, Nicholas P. Lockyer, Seetharaman Vaidyanathan, John C. Vickerman
Analytical Chemistry - 2007 -
ToF-SIMS analysis of bio-systems: Are polyatomic primary ions the
solution?
E. A. Jones, John S. Fletcher, C. E. Thompson, D. A. Jackson, N. P. Lockyer, J. C. Vickerman
Applied Surface Science - 2006 -
C-60, buckminsterfullerene: its impact on biological ToF-SIMS
analysis
John S. Fletcher, Nicholas P. Lockyer, John C. Vickerman
Surface and Interface Analysis - 2006 -
Molecular depth profiling of organic and biological
materials
John S. Fletcher, Xavier A. Conlan, Nicholas P. Lockyer, John C. Vickerman
Applied Surface Science - 2006 -
Rapid discrimination of the causal agents of urinary tract infection using ToF-SIMS with chemometric cluster
analysis
John S. Fletcher, A. Henderson, R. M. Jarvis, N. P. Lockyer, J. C. Vickerman, R. Goodacre
Applied Surface Science - 2006 -
TOF-SIMS analysis using C-60- effect of impact energy on yield and
damage
John S. Fletcher, X. A. Conlan, E. A. Jones, G. Biddulph, N. P. Lockyer, J. C. Vickerman
Analytical Chemistry - 2006 -
A comparative study of secondary ion yield from model biological membranes using Au-n(+) and C-60(+) primary ion
sources
M. J. Baker, John S. Fletcher, H. Jungnickel, N. P. Lockyer, J. C. Vickerman
Applied Surface Science - 2006 -
ToF-SIMS studies of Bacillus using multivariate analysis with possible identification and taxonomic
applications
C. E. Thompson, J. Ellis, John S. Fletcher, R. Goodacre, A. Henderson, N. P. Lockyer, J. C. Vickerman
Applied Surface Science - 2006 -
ToF-SIMS studies of Bacillus using multivariate analysis with possible identification and taxonomic
applications
Charlotte E. Thompson, Joanne Ellis, John S. Fletcher, Goodacre Roy, Alex Henderson, Nicholas P. Lockyer, John C. Vickerman
Applied Surface Science - 2006 -
ToF-SIMS Studies of Sulfuric Acid Hydrate
Films
John S. Fletcher, Alex Henderson, Andrew B. Horn, John C. Vickerman
Journal of Physical Chemistry B - 2004 -
ToF-SIMS analysis of atmospherically relevant sulphuric acid hydrate films and reactions
thereof
John S. Fletcher, John C. Vickerman
Applied Surface Science - 2004 -
First detection of molecular hydrate complexes in sulfuric acid
aerosols
SB Couling, John S. Fletcher, AB Horn, DA Newnham, RA McPheat, RG Williams
Physical Chemistry Chemical Physics - PCCP - 2003 -
Identification of surface molecular hydrates on solid sulfuric acid
films
SB Couling, KL Nash, John S. Fletcher, A Henderson, JC Vickerman, AB Horn
Journal of the American Chemical Society - 2003 -
The role of surface molecular hydrates in the heterogeneous interaction of NH3 with sulfuric acid
monohydrate
KL Nash, RM Sayer, SB Couling, John S. Fletcher, A Henderson, JC Vickerman, AB Horn
Physical Chemistry Chemical Physics - PCCP - 2003