Weixiao Yuan Wahlgren

Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP)

Michael J. Currie, James S. Davies, Mariafrancesca Scalise, Ashutosh Gulati, Joshua D. Wright, Michael C. Newton-Vesty, Gayan S. Abeysekera, Ramaswamy Subramanian, Weixiao Yuan Wahlgren, Rosmarie Friemann, Jane R. Allison, Peter D. Mace, Michael D. W. Griffin, Borries Demeler, Soichi Wakatsuki, David Drew, Cesare Indiveri, Renwick C. J. Dobson, Rachel A. North
ELIFE - 2024

Directed ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial

crystallography.

Andrea Cellini, Madan Kumar Shankar, Amke Nimmrich, Leigh Anna Hunt, Leonardo Monrroy, Jennifer Mutisya, Antonia Furrer, Emma V Beale, Melissa Carrillo, Tek Narsingh Malla, Piotr Maj, Lidija Vrhovac, Florian Dworkowski, Claudio Cirelli, Philip J M Johnson, Dmitry Ozerov, Emina A Stojković, Leif Hammarström, Camila Bacellar, Jörg Standfuss, Michał Maj, Marius Schmidt, Tobias Weinert, Janne A Ihalainen, Weixiao Yuan Wahlgren, Sebastian Westenhoff
Nature chemistry - 2024

Structural mechanism of signal transduction in a phytochrome histidine

kinase

Weixiao Yuan Wahlgren, Elin Claesson, Iida Tuure, Sergio Trillo-Muyo, Szabolcs Bódizs, Janne A. Ihalainen, Heikki Takala, Sebastian Westenhoff
Nature Communications - 2022

Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial

Growth

T. Bozzola, M. Scalise, C. U. Larsson, M. C. Newton-Vesty, C. Rovegno, A. Mitra, J. Cramer, Weixiao Yuan Wahlgren, P. R. Santhakumari, R. E. Johnsson, O. Schwardt, B. Ernst, Rosmarie Friemann, R. C. J. Dobson, C. Indiveri, J. Schelin, U. J. Nilsson, U. Ellervik
Acs Chemical Biology - 2022

Structural basis of the radical pair state in photolyases and

cryptochromes

Andrea Cellini, Madan K. Shankar, Weixiao Yuan Wahlgren, Amke Nimmrich, A. Furrer, D. James, M. Wranik, S. Aumonier, E. V. Beale, F. Dworkowski, J. Standfuss, T. Weinert, Sebastian Westenhoff
Chemical Communications - 2022

The three-dimensional structure of Drosophila melanogaster (6-4) photolyase at room

temperature

Andrea Cellini, Weixiao Yuan Wahlgren, Léocadie Henry, S. Pandey, Swagatha Ghosh, Leticia Castillon, Elin Claesson, H. Takala, Joachim Kübel, Amke Nimmrich, V. Kuznetsova, E. Nango, S. Iwata, S. Owada, E. A. Stojkovic, M. Schmidt, J. A. Ihalainen, Sebastian Westenhoff
Acta Crystallographica Section D-Structural Biology - 2021

High-resolution crystal structures of transient intermediates in the phytochrome

photocycle

M. Carrillo, S. Pandey, J. Sanchez, M. Noda, I. Poudyal, L. Aldama, T. N. Malla, Elin Claesson, Weixiao Yuan Wahlgren, D. Feliz, V. Srajer, Michal Maj, Leticia Castillon, S. Iwata, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, K. Tono, S. Owada, Sebastian Westenhoff, E. A. Stojkovic, M. Schmidt
Structure - 2021

Cryo-Electron Microscopy of Arabidopsis thaliana Phytochrome A in Its Pr State Reveals Head-to-Head Homodimeric

Architecture

Weixiao Yuan Wahlgren, D. Golonka, Sebastian Westenhoff, A. Moglich
Frontiers in Plant Science - 2021

Comparative analysis of two paradigm bacteriophytochromes reveals opposite functionalities in two-component

signaling

E. Multamaki, R. Nanekar, D. Morozov, T. Lievonen, D. Golonka, Weixiao Yuan Wahlgren, B. Stucki-Buchli, J. Rossi, V. P. Hytonen, Sebastian Westenhoff, J. A. Ihalainen, A. Moglich, H. Takala
Nature Communications - 2021

The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray

laser

Elin Claesson, Weixiao Yuan Wahlgren, H. Takala, S. Pandey, Leticia Castillon, V. Kuznetsova, Léocadie Henry, Matthijs R Panman, M. Carrillo, Joachim Kübel, R. Nanekar, Linnéa Isaksson, Amke Nimmrich, Andrea Cellini, D. Morozov, Michal Maj, M. Kurttila, Robert Bosman, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, S. Iwata, S. Owada, K. Moffat, G. Groenhof, E. A. Stojkovic, J. A. Ihalainen, M. Schmidt, Sebastian Westenhoff
eLife - 2020

Kinetic, Thermodynamic, and Crystallographic Studies of 2-Triazolylthioacetamides as Verona Integron-Encoded Metallo-beta-Lactamase 2 (VIM-2)

Inhibitor

Y. Xiang, Y. J. Zhang, Y. Ge, Y. J. Zhou, C. Chen, Weixiao Yuan Wahlgren, X. S. Tan, X. Chen, K. W. Yang
Biomolecules - 2020

Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase

1C3

M. L. Lolli, I. M. Carnovale, A. C. Pippione, Weixiao Yuan Wahlgren, D. Bonanni, E. Marini, D. Zonari, M. Gallicchio, V. Boscaro, Parveen Goyal, Rosmarie Friemann, B. Rolando, R. Bagnati, S. Adinolfi, S. Oliaro-Bosso, D. Boschi
Acs Medicinal Chemistry Letters - 2019

High-resolution crystal structures of amyxobacterial phytochrome at cryo and

roomtemperatures

J. C. Sanchez, M. Carrillo, S. Pandey, M. Noda, L. Aldama, D. Feliz, Elin Claesson, Weixiao Yuan Wahlgren, G. Tracy, P. Duong, A. C. Nugent, A. Field, V. Srajer, C. Kupitz, S. Iwata, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, K. Tono, S. Owada, Sebastian Westenhoff, M. Schmidt, E. A. Stojkovic
Structural Dynamics-Us - 2019

The sodium sialic acid symporter from Staphylococcus aureus has altered substrate

specificity

Rachel North, Weixiao Yuan Wahlgren, Daniela Remus, Mariafrancesca Scalise, Sarah Kessans, Elin Dunevall, Elin Claesson, Tatiana Soares da Costa, Matthew Perugini, S Ramaswamy, Jane Allison, Cesare Indiveri, Rosmarie Friemann, Renwick C. Dobson
Frontiers in Chemistry - 2018

Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+

site.

Weixiao Yuan Wahlgren, Elin Dunevall, Rachel A North, Aviv Paz, Mariafrancesca Scalise, Paola Bisignano, Johan Bengtsson-Palme, Parveen Goyal, Elin Claesson, Rhawnie Caing Carlsson, Rebecka Andersson, Konstantinos Beis, Ulf J Nilsson, Anne Farewell, Lorena Pochini, Cesare Indiveri, Michael Grabe, Renwick C J Dobson, Jeff Abramson, S Ramaswamy, Rosmarie Friemann
Nature Communications - 2018

Automation aided optimization of cloning, expression and purification of enzymes of the bacterial sialic acid catabolic and sialylation pathways enzymes for structural

studies.

Sneha Bairy, Lakshmi Narayanan Gopalan, Thanuja Gangi Setty, Sathya Srinivasachari, Lavanyaa Manjunath, Jay Prakash Kumar, Sai R Guntupalli, Sucharita Bose, Vinod Nayak, Swagatha Ghosh, Nitish Sathyanarayanan, Rhawnie Caing Carlsson, Weixiao Yuan Wahlgren, Rosmarie Friemann, S Ramaswamy, Muniasamy Neerathilingam
Microbial biotechnology - 2018

"Just a spoonful of sugar...": import of sialic acid across bacterial cell

membranes

Rachel A North, Christopher R Horne, James S Davies, Daniela M Remus, Andrew C Muscroft-Taylor, Parveen Goyal, Weixiao Yuan Wahlgren, S Ramaswamy, Rosmarie Friemann, Renwick C J Dobson
Biophysical reviews - 2018

Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic

acid.

Agnese Chiara Pippione, Irene Maria Carnovale, Davide Bonanni, Marcella Sini, Parveen Goyal, Elisabetta Marini, Klaus Pors, Salvatore Adinolfi, Daniele Zonari, Claudio Festuccia, Weixiao Yuan Wahlgren, Rosmarie Friemann, Renzo Bagnati, Donatella Boschi, Simonetta Oliaro-Bosso, Marco Lucio Lolli
European journal of medicinal chemistry - 2018

Asymmetry in serial femtosecond crystallography

data

Amit Sharma, Linda C Johansson, Elin Dunevall, Weixiao Yuan Wahlgren, Richard Neutze, Gergely Katona
Acta Crystallographica a-Foundation and Advances - 2017

Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter

McjD

K. Bountra, G. Hagelueken, H. G. Choudhury, V. Corradi, K. El Omari, A. Wagner, I. Mathavan, S. Zirah, Weixiao Yuan Wahlgren, D. P. Tieleman, O. Schiemann, S. Rebuffat, K. Beis
Embo Journal - 2017

Bayesian analysis of non-thermal structural changes induced by terahertz radiation in protein

crystals

Gergely Katona, Ida Lundholm, H. Rodilla, Maria-Jose Garcia-Bonete, Annette Duelli, Weixiao Yuan Wahlgren, G. Bourenkov, J. Vukusic, R. Friedman, T. Schneider, J. Stake
41st International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). SEP 25-30, 2016 .Copenhagen, Denmark. - 2016

Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein

crystal

Ida Lundholm, Helena Rodilla, Weixiao Yuan Wahlgren, Annette Duelli, Gleb Bourenkov, Josip Vukusic, Ran Friedman, Jan Stake, Thomas Schneider, Gergely Katona
Structural Dynamics - 2015

Applying THz Technology in Life

Science

Helena Rodilla, Josip Vukusic, Jan Stake, Anna Kim, Gavin Jeffries, Aldo Jesorka, Junsheng Yang, Ida Lundholm, Weixiao Yuan Wahlgren, Åsa Persson, Gergely Katona, Richard Neutze, Thomas Nyström, Andrew G Ewing
Swedish Microwave Days. Gigahertz Symposium, March 11-12, 2014. Gothenburg, Sweden - 2014

DYNLL2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5a Tail That Has Structural

Plasticity.

Andrea Bodor, László Radnai, Csaba Hetényi, Péter Rapali, András Láng, Katalin E Kövér, András Perczel, Weixiao Yuan Wahlgren, Gergely Katona, László Nyitray
Biochemistry - 2014

Terahertz absorption of illuminated photosynthetic reaction center solution: a signature of

photoactivation?

Ida Lundholm, Weixiao Yuan Wahlgren, F. Piccirilli, P. Di Pietro, Annette Duelli, Oskar Berntsson, S. Lupi, A. Perucchi, Gergely Katona
Rsc Advances - 2014

Structure of a photosynthetic reaction centre determined by serial femtosecond

crystallography.

Linda C Johansson, David Arnlund, Gergely Katona, Thomas A White, Anton Barty, Daniel P DePonte, Robert L Shoeman, Cecilia Wickstrand, Amit Sharma, Garth J Williams, Andrew Aquila, Michael J Bogan, Carl Caleman, Jan Davidsson, R Bruce Doak, Matthias Frank, Raimund Fromme, Lorenzo Galli, Ingo Grotjohann, Mark S Hunter, Stephan Kassemeyer, Richard A Kirian, Christopher Kupitz, Mengning Liang, Lukas Lomb, Erik Malmerberg, Andrew V Martin, Marc Messerschmidt, Karol Nass, Lars Redecke, M Marvin Seibert, Jennie Sjöhamn, Jan Steinbrener, Francesco Stellato, Dingjie Wang, Weixiao Yuan Wahlgren, Uwe Weierstall, Sebastian Westenhoff, Nadia A Zatsepin, Sébastien Boutet, John C H Spence, Ilme Schlichting, Henry N Chapman, Petra Fromme, Richard Neutze
Nature communications - 2013

Structural Insights at Sub-Ångstrom, Medium and Low Resolution: Crystallization of Trypsin, Bacterioferritin, Photosynthetic Reaction Center, and Photosynthetic Core

Complex

Weixiao Yuan Wahlgren
2012

Structural Characterization of Bacterioferritin from Blastochloris

viridis

Weixiao Yuan Wahlgren, Hadil Omran, D. von Stetten, A. Royant, Sjoerd van der Post, Gergely Katona
Plos One - 2012

Lipidic phase membrane protein serial femtosecond

crystallography.

Linda C Johansson, David Arnlund, Thomas A White, Gergely Katona, Daniel P DePonte, Uwe Weierstall, R Bruce Doak, Robert L Shoeman, Lukas Lomb, Erik Malmerberg, Jan Davidsson, Karol Nass, Mengning Liang, Jakob Andreasson, Andrew Aquila, Saša Bajt, Miriam Barthelmess, Anton Barty, Michael J Bogan, Christoph Bostedt, John D Bozek, Carl Caleman, Ryan Coffee, Nicola Coppola, Tomas Ekeberg, Sascha W Epp, Benjamin Erk, Holger Fleckenstein, Lutz Foucar, Heinz Graafsma, Lars Gumprecht, Janos Hajdu, Christina Y Hampton, Robert Hartmann, Andreas Hartmann, Günter Hauser, Helmut Hirsemann, Peter Holl, Mark S Hunter, Stephan Kassemeyer, Nils Kimmel, Richard A Kirian, Filipe R N C Maia, Stefano Marchesini, Andrew V Martin, Christian Reich, Daniel Rolles, Benedikt Rudek, Artem Rudenko, Ilme Schlichting, Joachim Schulz, M Marvin Seibert, Raymond G Sierra, Heike Soltau, Dmitri Starodub, Francesco Stellato, Stephan Stern, Lothar Strüder, Nicusor Timneanu, Joachim Ullrich, Weixiao Yuan Wahlgren, Xiaoyu Wang, Georg Weidenspointner, Cornelia Wunderer, Petra Fromme, Henry N Chapman, John C H Spence, Richard Neutze
Nature methods - 2012

The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease

action.

Weixiao Yuan Wahlgren, Gábor Pál, József Kardos, Pálma Porrogi, Borbála Szenthe, András Patthy, László Gráf, Gergely Katona
The Journal of biological chemistry - 2011

Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human

proteome.

Péter Rapali, László Radnai, Dániel Süveges, Veronika Harmat, Ferenc Tölgyesi, Weixiao Yuan Wahlgren, Gergely Katona, László Nyitray, Gábor Pál
PloS one - 2011

Lipidic sponge phase crystal structure of a photosynthetic reaction center reveals lipids on the protein

surface.

Annemarie Wöhri, Weixiao Yuan Wahlgren, Erik Malmerberg, Linda C Johansson, Richard Neutze, Gergely Katona
Biochemistry - 2009

A Lipidic-Sponge Phase Screen for Membrane Protein

Crystallization

Annemarie Wöhri, Linda C Johansson, Pia Wadsten-Hindrichsen, Weixiao Yuan Wahlgren, Gerhard Fischer, Rob Horsefield, Gergely Katona, Maria Nyblom, Fredrik Öberg, G Young, Richard Cogdell, N J Fraser, Sven Engström, Richard Neutze
Structure - 2008

Weixiao Yuan Wahlgren

Forskningsingenjör 1.e

Publikationer